Opioids Panel in Urine
Clinical Specimen Submission Guidance
Submit all specimens to 50 Orms St, Providence RI 02904. Open Monday to Friday 8:30 AM to 4:30 PM
Biomonitoring (401) 222-5552
Morphine-3Β-D-glucuronide, Morphine-6B-D-glucuronide, Morphine, Oxymorphone, Hydromorphone, Codeine-6B-D-glucuronide, Dihydrocodeine, Codeine, Oxycodone, 6-Acetylmorphine, O-desmethyl Tramadol, Hydrocodone, Norfentanyl, Tramadol, Norbuprenorphine, Fentanyl, Buprenorphine, EDDP, Methadone
Opioids Panel in Urine
Urine is extracted and analyzed by LC/MS/MS
All residual urine specimens from any hospital patient receiving treatment for a suspected overdose must be sent to the State Health Laboratories for confirmatory analysis
Non-Fatal Overdose
Collect urine in sterile cups within 48 hours. Optimal volume 4-7 mL, minimum volume 2 mL.
Freeze at -20°C ± 5° until transport to RISHL.
CLIA regulations require specimens be labeled with at least two patient identifiers. Examples of identifiers are first and last name, date of birth, chart/medical record number. The specimen container must be labeled to match the test requisition or the electronic order.
Rhode Island State Health Laboratories (RISHL) test requisition form https://health.ri.gov/forms/LabRequisitionForm.pdf
Opioids Panel
Refrigerated: Transport and deliver to the laboratory within 24 hours of collection at 2-8°C in a cooler able to maintain specimen temperature. A plug-in electric cooler is recommended, however, a cooler packed with excess frozen gel packs is acceptable as long as the transport temperature is maintained at 2-8°C.
Frozen: If specimen previously frozen, it must be transported on frozen gel packs in insulated shipper.
Specimens must be transported and packaged in accordance with current federal shipping regulations.
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