Opioids Panel in Urine
Clinical Specimen Submission Guidance
Submit all specimens to 150 Richmond Street, Suite 100, Providence, RI 02903. Open Monday to Friday 8:30 AM to 4:30 PM. Learn how and where to drop off your lab samples at our Laboratory Central Services webpage.
Biomonitoring (401) 222-5552
Morphine-3Β-D-glucuronide, Morphine-6B-D-glucuronide, Morphine, Oxymorphone, Hydromorphone, Codeine-6B-D-glucuronide, Dihydrocodeine, Codeine, Oxycodone, 6-Acetylmorphine, O-desmethyl Tramadol, Hydrocodone, Norfentanyl, Tramadol, Norbuprenorphine, Fentanyl, Buprenorphine, EDDP, Methadone
Opioids Panel in Urine
Urine is extracted and analyzed by LC/MS/MS
All residual urine specimens from any hospital patient receiving treatment for a suspected overdose must be sent to the State Health Laboratories for confirmatory analysis
Non-Fatal Overdose
Collect urine in sterile cups within 48 hours. Optimal volume 4-7 mL, minimum volume 2 mL.
Freeze at -20°C ± 5° until transport to RISHL.
CLIA regulations require specimens be labeled with at least two patient identifiers. Examples of identifiers are first and last name, date of birth, chart/medical record number. The specimen container must be labeled to match the test requisition or the electronic order.
Rhode Island State Health Laboratories (RISHL) test requisition form https://health.ri.gov/forms/LabRequisitionForm.pdf
Opioids Panel
Refrigerated: Transport and deliver to the laboratory within 24 hours of collection at 2-8°C in a cooler able to maintain specimen temperature. A plug-in electric cooler is recommended, however, a cooler packed with excess frozen gel packs is acceptable as long as the transport temperature is maintained at 2-8°C.
Frozen: If specimen previously frozen, it must be transported on frozen gel packs in insulated shipper.
Specimens must be transported and packaged in accordance with current federal shipping regulations.
The following rejection criteria will be used to ensure accurate specimen information and specimen condition for testing:
- Specimen received outside acceptable transport range
- Demographics different / Unable to read identifiers on specimen
- Two identifiers required on specimen
- Expired / Incorrect collection kit
- Insufficient quantity
- Urine cup received
- No specimen received
- Specimen leaked in transit
- Test not evaluated in adolescents <14
- Specimen too old
None detected