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Arbovirus (West Nile Virus)

Clinical Specimen Submission Guidance

Submit all specimens to 50 Orms St, Providence RI 02904. Open Monday to Friday 8:30 AM to 4:30 PM

Lab

STI & Arbovirus Laboratory 401-222-5591

Analyte Name

West Nile Virus

Disease

West Nile Virus

Test Description

An enzyme-linked immunosorbent capture assay to detect IgM antibodies to West Nile Virus.

All other requests for arbovirus testing are sent to CDC.

Special Instructions

Consult with the RIDOH Center for Acute Infectious Disease Epidemiology (401) 222-2577 for approval prior to transporting specimens.

Specimen

Serum: minimum 5 mL collected in red top tube

Cerebrospinal fluid (CSF): minimum 2 mL collected aseptically.

Acute serum and CSF should be collected within the first 14 days following onset of symptoms.

Refrigerate at 2° - 8° C

Virus isolation and/or nucleic amplification testing, acceptable specimens are fresh frozen tissue, serum, or cerebrospinal fluid. Tissue specimens should be approximately 1 x 3 cm, frozen as soon as possible at -70° C

Specimen Identification

CLIA regulations require specimens be labeled with at least two patient identifiers. Examples of identifiers are first and last name, date of birth, chart/medical record number. The specimen container must be labeled to match the test requisition or the electronic order.

Form Required

Rhode Island State Health Laboratories (RISHL) Test Requisition https://health.ri.gov/forms/LabRequisitionForm.pdf

Test Request

Write "WNV" under Comments/Other test requests

Transport

Refrigerated: Transport and deliver to the laboratory within 48 hours of collection at 2-8°C in a cooler able to maintain specimen temperature. A plug-in electric cooler is recommended, however, a cooler packed with excess frozen gel packs is acceptable as long as the transport temperature is maintained at 2-8°C. 

Frozen: If specimen previously frozen, it must be transported on frozen gel packs in insulated shipper.

Specimens must be transported and packaged in accordance with current federal shipping regulations.

Integrity

Non-Hemolyzed

Normal Value

Negative

Reporting Requirement

Providers must report patient information on West Nile Virus immediately using the RIDOH reportable disease form.

Turnaround Time

WNV: 5 Business Days

Confirmation testing performed at CDC

Kit

Containers specifically labeled for transport of specimens to the RISHL STI & Arbovirus Laboratory are available in all Serology Laboratories and Laboratory Sendout Departments.