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Norovirus

Clinical Specimen Submission Guidance

Submit all specimens to 50 Orms St, Providence RI 02904. Open Monday to Friday 8:30 AM to 4:30 PM

Lab

Molecular Diagnostics Laboratory 401-222-5538

Analyte Name

Norovirus

Disease

Norovirus

Test Description

Real-time reverse transcriptase polymerase chain reaction (RT-PCR)

Norovirus testing is performed using the FDA-approved Cepheid GeneXpert instrument for identification and differentiation of norovirus genogroup I and genogroup II.

Results should be used in conjunction with clinical evaluation, laboratory findings, and epidemiological information to determine an overall clinical diagnosis.

The performance characteristics were verified by the Rhode Island State Health Laboratories (RISHL).

Special Instructions

PREAUTHORIZATION by the RIDOH Center for Acute Infectious Disease Epidemiology (401) 222-2577 is required prior to transporting specimens.

Norovirus testing is for outbreak investigation only.

Specimen

Collect the unpreserved unformed stool specimen in a clean preservative-free vial: Minimum 5 mL 

Store refrigerated at 2- 8°C for up to 2 days.

CLIA regulations require two patient identifiers on the specimen container and the test requisition.

Form Required

Rhode Island State Health Laboratories (RISHL) test requisition form https://health.ri.gov/forms/LabRequisitionForm.pdf

Test Request

Norovirus PCR (outbreaks)

Transport

Transport within 24 hours of collection.

All specimens must be transported on wet ice or equivalent cooling material and packaged in accordance with current federal shipping regulations.

Integrity

Do not pass the specimen into toilet

Do not urinate in the specimen container

Do not take a laxative before collecting the specimen

Normal Value

Negative for Norovirus

Turnaround Time

2 business days

Kit

Kits may be obtained Monday - Friday between 8:30 am and 4:00 pm from the RI State Health Laboratories Center for Laboratory Support Services